top of page

RSO-021 Mechanism of Action

RSO-021 is a novel first-in-class small molecule that irreversibly binds mitochondrial PRX3.

This inhibition of the antioxidant signaling network results in selective killing of malignant cells by upregulation of oxidative stress; in contrast, healthy tissue is spared.

RS Oncology has identified a therapeutic approach that targets the sole waste removal system in the mitochondria.

PRX3-TS Model_NEW.png
bottom of page